HEPCIDIN AND HEPCIDIN ANTIBODIES

摘要

PROBLEM TO BE SOLVED: To provide purified, correctly folded hepcidin, and monoclonal antibodies that bind hepcidin.SOLUTION: There is provided an isolated monoclonal antibody which specifically binds to human hepcidin, where the human hepcidin consists of a specific amino acid sequence and has a conformation comprising four disulfide-bond loops formed between residues 7 and 23, 10 and 13, 11 and 19, and 14 to 22 located in the specific sequence.