Method for producing compounds comprising nitrile functions

摘要

The present invention concerns the production of compounds comprising nitrite functions and cyclic imide compounds. More specifically, the invention relates to the production of compounds comprising nitrile functions from compounds comprising carboxylic functions, advantageously of natural and renewable origin, and from methyl-2 glutaronitrile (MGN) or a mixture N of dinitriles comprising methyl-2 glutaronitrile (MGN), ethyl-2 succinonitrile (ESN) and adiponitrile (AdN).

主权项

1. A process for the preparation of at least one nitrile of general formula I:
(NC)v—R1—(CN)w  (I) or respectively of at least one nitrile of general formula III: or respectively of at least one nitrile of general formula V: and of at least the cyclic imide 3-methylglutarimide, by reaction between at least one carboxylic acid of general formula II:
(HOOC)x—R1—(COOH)z  (II) or respectively at least one carboxylic acid of general formula IV: or respectively at least one carboxylic acid of general formula VI: and one or more dinitriles, comprising at least 2-methylglutaronitrile (MGN), in the presence of a Lewis acid catalyst, wherein:
each of x, z is equal to 0 or 1 with (x+z) equal to 1 or 2,each of v, w is equal to 0 or 1 with (v+w) equal to 1 or 2,R1 represents a saturated or unsaturated and linear or branched hydrocarbon group which can comprise heteroatoms, comprising:
from 4 to 34 carbon atoms when (x+z) is equal to 2,from 2 to 22 carbon atoms when (x+z) is equal to 1,y is equal to 1 or 2, andR is hydroxyl, halo, alkyl, halo-alkyl, ether, thioether, acyl, aroyl, acyloxy, or aroyloxy.