| 发明名称 |
INHALABLE MEDICAMENT COMPRISING TIOTROPIUM |
| 摘要 |
This invention relates to a solution formulation containing a tiotropium salt, 12-20% ethanol, 0.1-1.5% of water, 0.05-0.10% citric acid (or other organic acid) and an HFA propellant, wherein the percentages are percentages by weight based on the total weight of the formulation. The invention also provides a pMDI comprising a canister containing the formulation. |
| 申请公布号 |
US2014348758(A1) |
申请公布日期 |
2014.11.27 |
| 申请号 |
US201214367031 |
申请日期 |
2012.12.06 |
| 申请人 |
TEVA Branded Pharmaceutical Products R&D, Inc. |
发明人 |
Zeng Xian-Ming |
| 分类号 |
A61K47/12;A61M15/00;A61K47/10;A61K31/439;A61K9/00 |
主分类号 |
A61K47/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A solution formulation comprising a tiotropium salt, 12-20% ethanol, 0.1 -1.5% of water, 0.05-0.10% citric acid and an HFA propellant, wherein the percentages are percentages by weight based on the total weight of the formulation. |
| 地址 |
Horsham PA US |
