| 主权项 |
1. A compound of formula (I), wherein: R1 is halo; R2 is halo; each R3 is independently cyano, haloalkyl, alkoxy, halo, haloalkoxy, hydroxy, amino, —NR6R9, —SR10, —C(O)R10, optionally substituted haloalkyl, optionally substituted arylalkoxy, —C(O)NR6R7, —CH(OH)-haloalkyl, optionally substituted alkyl, hydroxyalkyl, alkoxyalkyl, isocyano, cycloalkylaminocarbonyl, optionally substituted aryloxyalkyl, optionally substituted arylalkylthio, haloalkylthio, optionally substituted arylalkylsulfonyl, optionally substituted arylalkylsulfinyl, optionally substituted heteroarylalkoxy, optionally substituted arylthioalkyl, or haloalkylcarbonyl; n is 0, 1, 2 or 3; R4 is aryl optionally substituted with 0, 1, 2 or 3 independent R8; R5 is H, alkyl, phosphato, phosphito, alkoxyphosphato, or —C(O)alkyl optionally substituted with 1 or 2 amino; R6 is independently H or alkyl; R7 is independently H, optionally substituted alkyl, optionally substituted haloalkyl, or optionally substituted arylalkyl; each R8 is independently cyano, haloalkyl, alkoxy, halo, or haloalkoxy; each R9 is independently H, alkyl, —C(O)alkyl, —C(O)H, —C(O)haloalkyl, optionally substituted arylalkyl, or optionally substituted haloalkyl; each R10 is independently H, optionally substituted alkyl, optionally substituted aryl, optionally substituted heterocycloalkyl, or optionally substituted arylalkyl; Ar2 is R11 is optionally substituted phenyl, optionally substituted alkyl, optionally substituted thienyl, pyrrolyl, furanyl, optionally substituted pyridyl, —CH(OH)-alkyl, —CH(OH)-haloalkyl, optionally substituted arylalkyl, optionally substituted aryloxyalkyl, haloalkyl, haloalkoxyalkyl, optionally substituted indolyl, optionally substituted benzofuranyl, heterocycloalkyl, or R12 is R4, —C(O)R4, —C(O)R7, —SO2R4; MBG is optionally substituted tetrazolyl, optionally substituted triazolyl, optionally substituted oxazolyl, optionally substituted pyrimidinyl, optionally substituted thiazolyl, or optionally substituted pyrazolyl. |
