发明名称 |
A NUCLEAR RECEPTOR AND MUTANT THEREOF AND THE USE OF THE SAME IN THE REPROGRAMMING OF CELLS |
摘要 |
According to the invention there is provided methods for inducing pluripotent stem cells in vitro, comprising introducing a gene or polypeptide of a nuclear receptor and one or more gene or polypeptide selected from the group consisting of Sox, Krüppel-like factor or the myc family, to cells in vitro. The present invention also provides vectors and compositions for producing the same and methods for using the induced pluripotent stem cell for treating a patient in need of a pluripotent stem cell treatment. |
申请公布号 |
SG10201406139R(A) |
申请公布日期 |
2014.11.27 |
申请号 |
SG10201406139R |
申请日期 |
2010.09.30 |
申请人 |
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH |
发明人 |
HENG, DOMINIC JIAN-CHIEN;NG, HUCK HUI |
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