主权项 |
1. A compound of formula (I) in which A represents nitrogen or CR3,
whereR3 represents hydrogen, deuterium, fluorine, difluoromethyl, trifluoromethyl, (C1-C4)-alkyl, cyclopropyl or cyclobutyl, L represents a group *—CR4AR4B—(CR5AR5B)p-#,
where* represents the point of attachment to the carbonyl group,# represents the point of attachment to the pyrimidine or triazine ring,p represents a number 0, 1 or 2,R4A represents hydrogen, fluorine, (C1-C4)-alkyl or hydroxyl,R4B represents hydrogen, fluorine, (C1-C4)-alkyl, trifluoromethyl, (C1-C4)-alkoxy-carbonylamino or phenyl,
where (C1-C4)-alkyl may be substituted by 1 or 2 substituents independently of one another selected from the group consisting of fluorine, trifluoromethyl, hydroxyl, hydroxycarbonyl and (C1-C4)-alkoxycarbonyl,orR4A and R4B together with the carbon atom to which they are attached form an oxo group, a 3- to 6-membered carbocycle or a 4- to 6-membered heterocycle,
where the 3- to 6-membered carbocycle and the 4- to 6-membered heterocycle may be substituted by 1 or 2 substituents independently of one another selected from the group consisting of fluorine and (C1-C4)-alkyl,orR4A and R4B together with the carbon atom to which they are attached form a (C2-C4)-alkenyl group,R5A represents hydrogen, fluorine, (C1-C4)-alkyl or hydroxyl,R5B represents hydrogen, fluorine, (C1-C4)-alkyl or trifluoromethyl, R1 represents hydrogen or fluorine, R2 represents benzyl,
where benzyl is substituted by 1 to 3 fluorine substituents, or an N-oxide, salt, solvate, salt of the N-oxide, or and solvate of the N-oxide or salt thereof. |