发明名称 |
MULTI-FLUORESCENT SUBSTANCE INCLUDING NOVEL COUMARIN DERIVATIVE, AND LED LIGHT SOURCE-BASED MICROFLUORESCENT QUANTITATIVE BIOSENSOR FOR DIAGNOSIS USING SAME |
摘要 |
The present invention relates to a novel coumarin derivative, to a method for preparing the same, and a multi-fluorescent substance that includes a plurality of the coumarin derivatives and is able to emit light using an LED light source. A novel coumarin derivative multi-fluorescent substance according to the present invention has an optimal emission wavelength band of 512 nm to 590 nm and thereby is effective in improving a signal intensity and stability since light emission using an LED light source is possible.;In addition, higher fluorescence reactivity is exhibited compared to coumarin fluorescent substances known in the related arts since one molecule has a plurality of fluorescent substances, and the problem of the coumarin fluorescent substance possibly binding to a binding site of the antigen of the antibody is solved since fluorescence detection is possible even when a minimum number of fluorescent substance molecules bind to an antibody.;Moreover, the novel coumarin derivative multi-fluorescent substance according to the present invention is suitably used in a fluorescent-linked immunosorbent assay (FLISA) and a rapid fluorescent immunochromatographic test (FICT) as an LED-based microfluorescent quantitative biosensor for diagnosis, therefore, diseases such as malaria may be rapidly and quantitatively analyzed. |
申请公布号 |
US2014350227(A1) |
申请公布日期 |
2014.11.27 |
申请号 |
US201214350035 |
申请日期 |
2012.03.05 |
申请人 |
Park Hyun;Kim Hak Sung;Song Hyun Ok;Chong Chom Kyu;Kim Sung Yeon |
发明人 |
Park Hyun;Kim Hak Sung;Song Hyun Ok;Chong Chom Kyu;Kim Sung Yeon |
分类号 |
G01N33/58;C07D277/66 |
主分类号 |
G01N33/58 |
代理机构 |
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代理人 |
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主权项 |
1. A coumarin derivative represented by the compound of the following Chemical Formula 1, or a salt thereof: |
地址 |
Jeonju-si KR |