发明名称 |
IMMEDIATE RELEASE FORMULATIONS AND DOSAGE FORMS OF GAMMA-HYDROXYBUTYRATE |
摘要 |
The present invention provides a solid immediate release dosage form adapted for oral administration of GHB. The solid immediate release dosage form includes an immediate release formulation comprising a relatively high weight-percentage of GHB with a bioavailability similar to that of a liquid GHB dosage form. |
申请公布号 |
US2014348917(A1) |
申请公布日期 |
2014.11.27 |
申请号 |
US201414295098 |
申请日期 |
2014.06.03 |
申请人 |
Jazz Pharmaceuticals, Inc. |
发明人 |
Rourke Andrea Marie;Murphy Maura Patricia;Pfeiffer James Frederick;Allphin Clark Patrick;McGinlay Alya Kahn |
分类号 |
A61K9/20;A61K9/28;A61K31/19 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
1. An immediate release dosage form for oral delivery of GHB, the immediate release dosage form comprising:
an immediate release formulation comprising a pharmaceutically acceptable salt of GHB in an amount of at least 70% by weight of the immediate release formulation; and wherein the immediate release dosage form releases at least 90% of the GHB salt contained therein within a period of less than one hour after administration. |
地址 |
Palo Alto CA US |