CELL-BASED THERAPY FOR THE PULMONARY SYSTEM

摘要

Cell based therapy comprises administration to the lung by injection into the blood system of viable, mammalian cells effective for alleviating or inhibiting pulmonary disorders. The cells may express a therapeutic transgene or the cells may be therapeutic in their own right by inducing regenerative effects.

主权项

1. A process for alleviating or inhibiting the progression of mechanically induced acute lung injury in a mammalian patient comprising administration of syngeneic or allogeneic or autologous mesenchymal stem cells, smooth muscle cells, fibroblast cells or a combination thereof to the lung by injection into the pulmonary circulation of the mammalian patient suffering from the disorder wherein the administration results in alleviation or inhibition of the progression of the acute lung injury.