| 发明名称 |
SERPINA1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF |
| 摘要 |
The invention relates to RNAi agents, e.g., double- stranded RNAi agents, targeting the Serpinal gene, and methods of using such RNAi agents to inhibit expression of Serpinal and methods of treating subjects having a Serpinal associated disease, such as a liver disorder. |
| 申请公布号 |
WO2014190137(A1) |
申请公布日期 |
2014.11.27 |
| 申请号 |
WO2014US39109 |
申请日期 |
2014.05.22 |
| 申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
SEHGAL, ALFICA;CHARISSE, KLAUS;BETTENCOURT, BRIAN |
| 分类号 |
C12N15/113;A61K31/712;A61K31/713;A61P1/16;A61P11/00;A61P35/00 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
