发明名称 |
THYMIC STROMAL LYMPHOPOIETIN FRAGMENTS AND USES THEREOF |
摘要 |
The present invention relates to a compound selected in the group consisting of: a) a polypeptide consisting of the C-terminus amino acid sequence of the human Thymic stromal lymphopoietin (TSLP) long isoform (SEQ ID NO: 2), derivatives and fragments thereof; b) a polynucleotide coding for said polypeptide; d) a vector comprising said polynucleotide; c) a host cell genetically engineered expressing said polypeptide, or d) a TSLP long isoform (SEQ ID NO:2) antagonist for use in the treatment or/and prevention and/or diagnosis and/or monitoring of a disorder or pathology characterized by an inflammatory response. |
申请公布号 |
WO2014162007(A3) |
申请公布日期 |
2014.11.27 |
申请号 |
WO2014EP56878 |
申请日期 |
2014.04.04 |
申请人 |
IEO - ISTITUTO EUROPEO DI ONCOLOGIA SRL |
发明人 |
RESCIGNO, MARIA;PENNA, GIUSEPPE;TSILINGIRI, KATERINA;FORNASA, GIULIA |
分类号 |
A61K38/19;A61K39/395;G01N33/50 |
主分类号 |
A61K38/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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