发明名称 THYMIC STROMAL LYMPHOPOIETIN FRAGMENTS AND USES THEREOF
摘要 The present invention relates to a compound selected in the group consisting of: a) a polypeptide consisting of the C-terminus amino acid sequence of the human Thymic stromal lymphopoietin (TSLP) long isoform (SEQ ID NO: 2), derivatives and fragments thereof; b) a polynucleotide coding for said polypeptide; d) a vector comprising said polynucleotide; c) a host cell genetically engineered expressing said polypeptide, or d) a TSLP long isoform (SEQ ID NO:2) antagonist for use in the treatment or/and prevention and/or diagnosis and/or monitoring of a disorder or pathology characterized by an inflammatory response.
申请公布号 WO2014162007(A3) 申请公布日期 2014.11.27
申请号 WO2014EP56878 申请日期 2014.04.04
申请人 IEO - ISTITUTO EUROPEO DI ONCOLOGIA SRL 发明人 RESCIGNO, MARIA;PENNA, GIUSEPPE;TSILINGIRI, KATERINA;FORNASA, GIULIA
分类号 A61K38/19;A61K39/395;G01N33/50 主分类号 A61K38/19
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