SYSTEMS AND METHODS FOR ONE OR MORE OF DETECTING, ISOLATING, IDENTIFYING, TRANSPORTING AND QUANTIFYING A TARGET ANALYTE IN A FLUID

摘要

A system for one or more of detecting, isolating, identifying, transporting, and quantifying a target analyte in a fluid suspected of containing the target analyte. The system includes a magnetic nanocomposite having one or more selectively magnetic nanoparticles in a first nanocontainer, and a first binding moiety linked to the first nanocontainer and adapted to specifically bind the target analyte, and a luminescent nanocomposite having one or more selectively luminescent nanoparticles in a second nanocontainer, and a second binding moiety linked to the second nanocontainer and adapted to specifically bind the target analyte. The magnetic nanocomposite and the luminescent nanocomposite do not specifically bind to each other in the absence of the target analyte. The first and second binding moieties may be adapted to simultaneously bind the target analyte to form a magnetic luminescent nanoassembly.

主权项

1. A system for one or more of detecting, isolating, identifying, transporting, and quantifying a target analyte in a fluid suspected of containing the target analyte, the system comprising:
a magnetic nanocomposite comprising one or more selectively magnetic nanoparticles in a first nanocontainer, and a first binding moiety linked to the first nanocontainer and adapted to specifically bind the target analyte; and a luminescent nanocomposite comprising one or more selectively luminescent nanoparticles in a second nanocontainer, and a second binding moiety linked to the second nanocontainer and adapted to specifically bind the target analyte; wherein the magnetic nanocomposite and the luminescent nanocomposite do not specifically bind to each other in the absence of the target analyte, and wherein the first and second binding moieties are adapted to simultaneously bind the target analyte to form a magnetic-luminescent nanoassembly.