发明名称 |
SYSTEMS AND METHODS FOR COUNTING CELLS AND BIOMOLECULES |
摘要 |
The present invention generally relates to systems and methods for counting biomolecules or cells. In certain embodiments, the invention provides a cell counting or biomolecule counting system including: a covered chamber having a known height and configured to hold a suspension of biomolecules or cells in a sample; at least one fluorescent light source connected to at least one fluorescent light beam narrowing device; a bright-field light source connected to a bright-field light beam narrowing device; a microscope objective; a detection device; a fluorescent filter assembly to allow only excitation light to illuminate the sample and allow only emission light from the sample to be imaged by the detection device; and a movable light shutter to block bright-field light during fluorescent detection. |
申请公布号 |
US2014347463(A1) |
申请公布日期 |
2014.11.27 |
申请号 |
US201414452612 |
申请日期 |
2014.08.06 |
申请人 |
NEXCELOM BIOSCIENCE LLC |
发明人 |
Lin Bo;Li Peter Y.;Qiu Jean;Smith Timothy;Sobolewski Todd;Pirani Alnoor |
分类号 |
G06K9/00;G02B21/16;G02B21/06;G01N33/487;G02B21/36 |
主分类号 |
G06K9/00 |
代理机构 |
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代理人 |
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主权项 |
1. A system for counting cells or biomolecules comprising:
a covered chamber having a known height and configured to hold a suspension of biomolecules or cells in a sample; at least one fluorescent light source connected to at least one fluorescent light beam narrowing device; a bright-field light source connected to a bright-field light beam narrowing device; a microscope objective; a detection device; a fluorescent filter assembly to allow only excitation light to illuminate the sample and allow only emission light from the sample to be imaged by the detection device; and a movable light shutter to block bright-field light during fluorescent detection. |
地址 |
Lawrence MA US |