Diaminopyrimidines as P2X3 and P2X2/3 antagonists

摘要

DIAMINOPYRIMIDINES AS P2X3 AND P2X2/3 ANTAGONISTS Abstract Compounds and methods for treating diseases mediated by a P2X 3 and/or a P2X 2/3 receptor antagonists, the methods comprising administering to a subject in need thereof an s effective amount of a compound of formula (I) or a pharmaceutically acceptable salt, solvate or prodrug thereof, wherein D, X, Y, R', R , R', R', R', R', R' and R' are as defined herein.