| 摘要 |
<p>PROBLEM TO BE SOLVED: To provide a method of predicting a favorable response to p53 gene therapy for a human subject having a tumor.SOLUTION: The method includes (a) determining whether tumor cells of the tumor comprise at least one wild-type p53 allele; and/or (b) determining whether tumor cells of the tumor express p53 protein at a level that is higher than that expressed in normal p53-expressing non-tumor cells.</p> |
