摘要 |
Compositions and methods for treatment and prevention of disorders and conditions characterized by reduced TGF-B signaling are described. In particular, the compositions and methods are useful for reducing or eliminating the pathologies associated with Alzheimer's disease. The compositions include urea derivatives containing a piperidine, piperidinium, or a piperidin-4-yl methyl; cycloalkyl, aryl, and fluorobenzyl moieties. |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;SRI INTERNATIONAL |
发明人 |
TANGA, MARY, JEAN;BEAULIEU, LAURA, ELLEN DOWNS;RYAN, KENNETH, JOSEPH;WYSS-CORAY, ANTON;GREEN, CAROL |