SINGLE-USE MIXING AND BIOREACTOR SYSTEMS

摘要

Disclosed are magnetic agitation mixing systems for use with flexible container reaction vessels. In one aspect of the invention, the orientation of magnetic coupling between the impeller magnets and the external driver magnets is modified such that the coupling is neither strictly axial nor strictly radial. Also disclosed are “receiver-less” retainer configurations whereby the single-use container need not have a rigid base that defines a cup or post to engage of rotatable agitator.

主权项

1. A mixing system comprising:
a flexible bag (128) for containing a fluid; a magnetic agitator (142) disposable in the bag (128) for mixing the fluid, the agitator (142) configured to rotate about an axis of rotation when magnetically coupled to an external magnetic drive system (121); wherein the flexible bag is configured to be supported by a bag support structure (104) including a bag support structure wall (106) that at least partially surrounds, supports or contains the bag (128) during use and the flexible bag (128) is further adapted for deformation by a shaped portion of the bag support structure (104) to define a receiverless retainer for the agitator (142) within the bag (128) when the agitator (142) is magnetically coupled to the external magnetic drive system (121).