| 发明名称 |
SOLUBLE ST2 AS A MARKER FOR RISK OF MORTALITY IN HIV-INFECTED SUBJECTS |
| 摘要 |
The present invention relates to materials and methods concerning the IL-1 receptor family protein ST2. Use of soluble ST2 as a marker for cardiovascular disease or disease outcome is provided, in particular as a marker of the risk of mortality. |
| 申请公布号 |
US2014349324(A1) |
申请公布日期 |
2014.11.27 |
| 申请号 |
US201214365340 |
申请日期 |
2012.12.14 |
| 申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) ;UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE |
发明人 |
Levy Yves |
| 分类号 |
G01N33/68 |
主分类号 |
G01N33/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of predicting the risk of mortality of a HIV-infected subject comprising
(i) determining the level of sST2 in a biological sample from said subject; and (ii) comparing said level of ST2 with a control level wherein a level of sST2 in the subject sample which is higher than that of the control is indicative of an increased risk of mortality. |
| 地址 |
Paris FR |
