| 发明名称 |
<sp>18</sp>F-LABELLED FOLATE/ANTIFOLATE ANALOGUES |
| 摘要 |
<p>The present invention is directed towards new 18F-folate/antifolate analogue radiopharmaceuticals, wherein the phenyl group within folate structures has been replaced by an 18F-heterocycle, their precursors, a method of their preparation, as well as their use in diagnosis of a cell or population of cells expressing a folate-receptor and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.</p> |
| 申请公布号 |
SG11201406481T(A) |
申请公布日期 |
2014.11.27 |
| 申请号 |
SGT11201406481 |
申请日期 |
2013.05.08 |
| 申请人 |
MERCK & CIE |
发明人 |
SCHIBLI, ROGER;MOSER, RUDOLF;MÜLLER, CRISTINA MAGDALENA;AMETAMEY, SIMON MENSAH;BETZEL, THOMAS;GROEHN, VIOLA |
| 分类号 |
C07D475/04;A61K31/522;A61K51/04;C07B59/00 |
主分类号 |
C07D475/04 |
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