| 发明名称 |
BIOMEDICAL MATERIALS |
| 摘要 |
The present invention provides a process for the preparation of a silicate and carbonate co-substituted calcium phosphate material. The process comprises the steps of: forming a silicon and optionally carbon-containing calcium phosphate precipitate by an aqueous precipitation method involving preparing an aqueous solution comprising phosphate ions, silicate ions, calcium ions and optionally carbonate ions, wherein the ratio of Ca/P and of Ca/(P+Si) in the solution is maintained above approximately 1.67; and heating the precipitate in an atmosphere comprising carbon and oxygen to form a silicate and carbonate co-substituted calcium phosphate material.;The present invention also provides a synthetic carbonate and silicate co-substituted hydroxyapatite material, as well as a biomedical material. |
| 申请公布号 |
US2014348943(A1) |
申请公布日期 |
2014.11.27 |
| 申请号 |
US201414274014 |
申请日期 |
2014.05.09 |
| 申请人 |
The University Court of the University of Aberdeen ;ApaTech Limited |
发明人 |
Gibson Iain R.;Skakle Janet M.S.;Hadden Daniel J.;Buckland Thomas |
| 分类号 |
A61L27/12;A61L27/02 |
主分类号 |
A61L27/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A process for the preparation of a silicate and carbonate co-substituted calcium phosphate material, which process comprises:
forming a silicon and optionally carbon-containing calcium phosphate precipitate by an aqueous precipitation method involving preparing an aqueous solution comprising phosphate ions, silicate ions, calcium ions and optionally carbonate ions, wherein the ratio of Ca/P and of Ca/(P+Si) in the solution is maintained above approximately 1.67; and heating the precipitate in an atmosphere comprising carbon and oxygen to form a silicate and carbonate co-substituted calcium phosphate material. |
| 地址 |
Aberdeen GB |
