BIOCOMPATIBLE X-RAY OPAQUE POLYMERS FOR MEDICAL DEVICE

摘要

The present application relates to a radio opaque material and a method of producing the same. The material is a hybrid material comprising two phases, an inorganic phase comprising a radio opaque substance and a polymer phase.

主权项

1. A sol-gel method of producing a hybrid material comprising two phases; a first and a second phase wherein the first phase comprises an inorganic compound and the second phase comprises a biodegradable polymer, where the method comprises the steps of:
providing a first solution comprising an inorganic precursor comprising at least one metal alkoxide compound that is radio opaque, and a first solvent; providing a second solution comprising a biodegradable polyether polymer and a second solvent miscible with the first solvent; forming a mixture by mixing the first and the second solutions; bringing the mixture in contact with liquid water or water in vapor phase; letting the liquid water or water in vapor phase react with the metal alkoxide to form a sol; letting the liquid water or water in vapor phase react further with the metal alkoxide to form a gel; and removing the solvents to form a solid material.