| 发明名称 |
Variants derived from ActRIIB and uses therefor |
| 摘要 |
The present invention provides a variant ActRIIB protein comprising an amino acid sequence that is at least 90% identical to amino acids 29-109 of SEQ ID NO:2, wherein the protein comprises an acidic amino acid at the position corresponding to position 79 of SEQ ID NO: 2. |
| 申请公布号 |
EP2805967(A1) |
申请公布日期 |
2014.11.26 |
| 申请号 |
EP20140175663 |
申请日期 |
2008.02.04 |
| 申请人 |
ACCELERON PHARMA, INC. |
发明人 |
KNOPF, JOHN;KUMAR, RAVINDRA;SEEHRA, JASBIR |
| 分类号 |
C07K14/705;A61K38/00;A61K38/17;C07K14/71;C07K14/72;C07K16/18 |
主分类号 |
C07K14/705 |
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