发明名称 |
Nicotinamide riboside and analogues thereof |
摘要 |
<p>Provided herein are sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.</p> |
申请公布号 |
EP2805719(A1) |
申请公布日期 |
2014.11.26 |
申请号 |
EP20140169305 |
申请日期 |
2006.03.30 |
申请人 |
GLAXOSMITHKLINE LLC |
发明人 |
MILBURN, MICHAEL;MILNE, JILL;NORMINGTON, KARL, D;NUNES, JOSEPH, J;SALZMANN, THOMAS;SINCLAIR, DAVID;WESTPHAL, CHRISTOPH, H |
分类号 |
A61K31/445;A61P39/00;C07H7/06;C07H19/048 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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