| 摘要 |
Disclosed is an inhibitor which can inhibit at least two vesicular neurotransmitter transporters for excitatory neurotransmitters under a chloride concentration included in physiological conditions. Also disclosed is a novel method for the screening of the inhibitor. The inhibitor is useful for the treatment of epilepsy, inflammations, tremor, pain, hypertension, ischemia, Parkinson's disease, Alzheimer's disease, osteopetrosis, osteoporosis or the like. Further disclosed is a method for the screening of a substance capable of activating a suppressed vesicular neurotransmitter transporter. |
