发明名称 |
METHOD FOR TREATING FATTY LIVER DISEASES, IN PARTICULAR NON-ALCOHOLIC STEATOHEPATITIS. |
摘要 |
The invention is in the field of medical treatments of liver disease, in particular non-alcoholic fatty liver diseases, such as non-alcoholic steatohepatitis. The invention provides a composition comprising an effective amount of a compound capable of increasing the intracellular level of 27-hydroxycholesterol for the treatment of liver inflammation in fatty liver disease. It also provides a method of reducing liver inflammation in a patient with non-alcoholic fatty liver disease by administering an effective amount of 27-hydroxycholesterol. |
申请公布号 |
EP2603096(B1) |
申请公布日期 |
2014.11.26 |
申请号 |
EP20110749368 |
申请日期 |
2011.07.30 |
申请人 |
UNIVERSITEIT MAASTRICHT;ACADEMISCH ZIEKENHUIS MAASTRICHT |
发明人 |
SVERDLOV, RONIT;BIEGHS, VEERLE;GORP, VAN, PATRICK, JOHANNES, JACOBUS |
分类号 |
A23L1/30;A61K31/575;A61P1/16 |
主分类号 |
A23L1/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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