发明名称 METHOD FOR TREATING FATTY LIVER DISEASES, IN PARTICULAR NON-ALCOHOLIC STEATOHEPATITIS.
摘要 The invention is in the field of medical treatments of liver disease, in particular non-alcoholic fatty liver diseases, such as non-alcoholic steatohepatitis. The invention provides a composition comprising an effective amount of a compound capable of increasing the intracellular level of 27-hydroxycholesterol for the treatment of liver inflammation in fatty liver disease. It also provides a method of reducing liver inflammation in a patient with non-alcoholic fatty liver disease by administering an effective amount of 27-hydroxycholesterol.
申请公布号 EP2603096(B1) 申请公布日期 2014.11.26
申请号 EP20110749368 申请日期 2011.07.30
申请人 UNIVERSITEIT MAASTRICHT;ACADEMISCH ZIEKENHUIS MAASTRICHT 发明人 SVERDLOV, RONIT;BIEGHS, VEERLE;GORP, VAN, PATRICK, JOHANNES, JACOBUS
分类号 A23L1/30;A61K31/575;A61P1/16 主分类号 A23L1/30
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