发明名称 SUBSTITUTED TRIAZOLES AND THEIR USE FOR TREATMENT AND/OR PREVENTION OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS
摘要 <p>This invention relates to compounds of formula I their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. A, B, Ar, R1, R2, R3 have meanings given in the description.</p>
申请公布号 EP2804854(A1) 申请公布日期 2014.11.26
申请号 EP20130700710 申请日期 2013.01.16
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 GRAUERT, MATTHIAS;BISCHOFF, DANIEL;DAHMANN, GEORG;KUELZER, RAIMUND;RUDOLF, KLAUS
分类号 C07D249/08;A61K31/4196;A61P25/18;A61P25/28;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D405/14 主分类号 C07D249/08
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