发明名称 |
MANUFACTURE OF BOOSTER VACCINES HAVING REDUCED ANTIGEN DOSES |
摘要 |
<p>A process for manufacturing a vaccine, wherein the vaccine comprises diphtheria toxoid and tetanus toxoid and, and wherein the process comprises steps of combining (i) a first bulk comprising diphtheria toxoid and tetanus toxoid with (ii) a second bulk comprising tetanus toxoid but no diphtheria toxoid. This arrangement facilitates convenient manufacture of both pediatric and adolescent vaccines from the same bulks: the first bulk can have a diphtheriartetanus ratio that is suitable for pediatric vaccines, and the second bulk can be used to reduce the relative amount of diphtheria toxoid, as found in the adolescent vaccines.</p> |
申请公布号 |
EP2073841(B1) |
申请公布日期 |
2014.11.26 |
申请号 |
EP20070825522 |
申请日期 |
2007.08.15 |
申请人 |
GLAXOSMITHKLINE BIOLOGICALS S.A. |
发明人 |
DE HEYDER, KOENRAAD;ARTOIS, CLAUDE;VANDECASSERIE, CHRISTIAN |
分类号 |
A61K39/295;A61K39/05;A61K39/08;A61K39/10;A61K39/13;A61K39/29 |
主分类号 |
A61K39/295 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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