发明名称 ALDOSTERONE SYNTHASE INHIBITORS
摘要 This invention relates to tricyclic triazole analogs of the formula I or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthetase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthetase.
申请公布号 EP2701512(A4) 申请公布日期 2014.11.26
申请号 EP20120776492 申请日期 2012.04.20
申请人 MERCK SHARP & DOHME CORP.;ELEXOPHARM GMBH 发明人 HOYT, SCOTT, B.;PETRILLI, WHITNEY LANE;LONDON, CLARE;XIONG, YUSHENG;TAYLOR, JERRY ANDREW;ALI, AMJAD;LO, MICHAEL;HENDERSON, TIMOTHY, J.;HU, QINGZHONG;HARTMANN, ROLF;YIN, LINA;HEIM, RALF;BEY, EMMANUEL;SAXENA, ROHIT;SAMANTA, SWAPAN KUMAR;KULKARNI, BHEEMASHANKAR, A.
分类号 A01N43/64;A61K31/41;A61K45/06;C07D471/04;C07D487/04;C07D519/00 主分类号 A01N43/64
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