Punctal plugs with directional release

摘要

Disclosed are lacrimal inserts and their method of use for delivery of medication to the eye. The plug includes a body portion sized to pass through a lacrimal punctum and be positioned within a lacrimal canaliculus of the eyelid and includes means for directional release of medication into the lacrimal fluid. The plug may contain a core, or reservoir, at least partially within the body portion comprising a therapeutic agent that is configured to controlled release into the eye.

主权项

1. A lacrimal insert, comprising:
a body having a first end and a second end; a surface extending between the two ends; a reservoir contained within the body, wherein the reservoir comprises at least one opening, an active agent-containing material and an active agent;
a directional release feature connected to the second end; and a channel running though the directional release feature from the reservoir to an end of the directional release feature and configured to direct the active agent into lacrimal fluid.