发明名称 |
DUPLEX OLIGONUCLEOTIDE COMPLEXES AND METHODS FOR GENE SILENCING BY RNA INTERFERENCE |
摘要 |
Provided herein are duplex oligonucleotide complexes which can be administered to a cell, tissue or organism to silence a target gene without the aid of a transfection reagent(s). The duplex oligonucleotide complexes of the disclosure include a conjugate moiety that facilitates delivery to a cell, tissue or organism. |
申请公布号 |
CA2663601(C) |
申请公布日期 |
2014.11.25 |
申请号 |
CA20072663601 |
申请日期 |
2007.09.20 |
申请人 |
DHARMACON, INC. |
发明人 |
YAMADA, CHRISTINA;KHVOROVA, ANASTASIA;KAISER, ROB;ANDERSON, EMILY;LEAKE, DEVIN |
分类号 |
C12N15/11;A61K31/713;A61K47/48;C07H21/00;C07H21/02;C12N15/87 |
主分类号 |
C12N15/11 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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