| 发明名称 | Monoclonal antibodies to influenza H1N1 virus uses thereof | ||
| 摘要 | The present invention is directed to particular monoclonal antibodies and fragments thereof that find use in the detection, prevention and treatment of influenza virus infections. In particular, these antibodies may neutralize or limit the replication of H1N1 influenza virus. Also disclosed are improved methods for producing such monoclonal antibodies. | ||
| 申请公布号 | US8894997(B2) | 申请公布日期 | 2014.11.25 |
| 申请号 | US201013318020 | 申请日期 | 2010.04.30 |
| 申请人 | Vanderbilt University;Icahn School of Medicine at Mount Sinai | 发明人 | Crowe James E.;Basler Christopher F. |
| 分类号 | A61K39/395;A61K39/42;A61K39/00;C12N15/74;C07K16/00;G01N33/569;C07K16/10;A61K39/145 | 主分类号 | A61K39/395 |
| 代理机构 | Parker Highlander PLLC | 代理人 | Parker Highlander PLLC |
| 主权项 | 1. An expression vector comprising a nucleic acid molecule encoding a heavy chain variable region comprising the sequence of SEQ ID NO: 7. | ||
| 地址 | Nashville TN US | ||