Gallium-68 radioisotope generator and generating method thereof

摘要

A Gallium-68 (Ga-68) radioisotope generator includes a generating column and a citrate eluent. The generating column is at least partially filled with an ion-exchange resin with glucamine groups to absorb germanium-68 (Ge-68) and Ga-68 radioisotopes. The citrate eluent is added into the generating column to desorb the Ga-68 radioisotope and form an eluent containing the Ga-68 radioisotope in the form of Ga-68 citrate. A method for generating Ga-68 radioisotope is also disclosed.

主权项

1. A method for generating gallium-68 radioisotope comprising the steps of:
providing a generating column at least partially filled with an ion-exchange resin with glucamine groups; adding an alkaline eluate containing the germanium-68 radioisotope into the generating column to absorb the germanium-68 radioisotope by the ion exchange resin with glucamine groups; creating gallium-68 radioisotope front the decay of the germanium-68 radioisotope in the generating column; adding a citrate eluent into the generating column; and providing a transforming column connected to an outlet of the generating column and at least partially filled with a silicone gel to absorb the gallium-68 radioisotope.