High throughout reproducible cantilever functionalization

摘要

A method for functionalizing cantilevers is provided that includes providing a holder having a plurality of channels each having a width for accepting a cantilever probe and a plurality of probes. A plurality of cantilever probes are fastened to the plurality of channels of the holder by the spring clips. The wells of a well plate are filled with a functionalization solution, wherein adjacent wells in the well plate are separated by a dimension that is substantially equal to a dimension separating adjacent channels of the plurality of channels. Each cantilever probe that is fastened within the plurality of channels of the holder is applied to the functionalization solution that is contained in the wells of the well plate.

主权项

1. A method for functionalizing cantilevers comprising:
providing a holder comprising a plurality of channels each having a width for accepting a cantilever probe and a plurality of clips each having a beam extending over the plurality of channels; fastening a plurality of cantilever probes to the plurality of channels of the holder, wherein each cantilever probe of the plurality of cantilever probes is fastened within each channel of the plurality of channels by the beam for each of the plurality of clips; filling wells that are present in a well plate with a functionalization solution, wherein adjacent wells in the well plate are separated by a dimension that is substantially equal to a dimension separating adjacent channels of the plurality of channels; and applying said each cantilever probe of said plurality of cantilever probes that are fastened within the plurality of channels of the holder into the wells containing the functionalization solution that is present in the well plate.