| 发明名称 | Combined fibrinolytic and antimicrobial catheter and uses thereof | ||
| 摘要 | Implantable catheters are provided which comprise an antimicrobial agent incorporated in a coating or bulk distributed, in combination with a fibrinolytic agent incorporated in a top coating. | ||
| 申请公布号 | US8895047(B2) | 申请公布日期 | 2014.11.25 |
| 申请号 | US200812451773 | 申请日期 | 2008.05.21 |
| 申请人 | Arrow International, Inc. | 发明人 | Gupta Nisha;Rosenblatt Joel;Spangler Daniel J. |
| 分类号 | A61F2/00;A61K38/49;A61K31/155;A61K31/135;A61K31/65;A61K31/497;A61L33/00;A61L29/16;A61K38/48;A61M25/00 | 主分类号 | A61F2/00 |
| 代理机构 | Baker & Hostetler LLP | 代理人 | Baker & Hostetler LLP |
| 主权项 | 1. An implantable catheter comprising, in combination, an antimicrobial agent that comprises chlorhexidine incorporated in a coating or bulk distributed combined with urokinase incorporated in a top coating, wherein the chlorhexidine does not decrease the fibrinolytic activity of the urokinase, and wherein the ratio of chlorhexidine/urokinase is 20/1 (weight/weight). | ||
| 地址 | Reading PA US | ||