Aptamers for <i>clostridium difficile </i>diagnostics

摘要

The present disclosure relates generally to the field of nucleic acids and, more particularly, to aptamers capable of binding to toxins produced by Clostridium difficile; diagnostic kits and methods comprising such aptamers; and methods of making and using such aptamers.

主权项

1. A method of detecting the presence of C. difficle toxin in a test sample comprising contacting said test sample with an aptamer that binds to C. difficile toxin B wherein said aptamer comprises a sequence selected from the group consisting of SEQ ID NOS: 67-71.