发明名称 Methods for inhibiting the development of huntington's disease
摘要 This invention relates to Huntington's disease and more specifically to methods for inhibiting the development of or treating Huntington's disease by administering estrogen, testosterone, precursors thereof or combinations thereof.
申请公布号 US8895541(B2) 申请公布日期 2014.11.25
申请号 US201012961250 申请日期 2010.12.06
申请人 发明人 Carnazza James A.
分类号 A61K31/565;A61P25/00 主分类号 A61K31/565
代理机构 AGG Intellectual Property Law 代理人 Giugliano Antoinette G.;AGG Intellectual Property Law
主权项 1. A method of treating a female individual having Huntington's Disease (HD) or a female individual having an HD gene having a number of CAG repeats greater than or equal to about 36; the method comprising: a. selecting a female individual having HD or an HD gene having a number of CAG repeats greater than or equal to about 36; b. administering to the female individual an amount of 17β-estradiol, wherein the amount of administration to the female individual ranges from about 0.2 mg to about 10 mg; wherein the individual with HD or HD gene having a number of CAG repeats greater than or equal to about 36 is treated.
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