Implantable MEMs intraocular pressure sensor devices and methods for glaucoma monitoring

摘要

An implantable device for measuring IOP comprises a distal portion, a proximal portion and a conformable elongate support extending between the distal and proximal portions. The distal portion comprises a pressure sensor, for example a capacitor, and the proximal portion comprises a coil. The conformable elongate support extends between the distal portion and the coil so as to couple the distal portion to the coil, and the conformable elongate support is sized to position the sensor in the anterior chamber when the proximal portion is positioned under a conjunctiva of the eye. Positioning of the pressure sensor in the anterior chamber has the benefit of readily accessible surgical access and a direct measurement of the IOP of the eye. The proximal portion comprising the coil can be configured to place the coil between the sclera and the conjunctiva, such that the invasiveness of the surgery can be decreased substantially.

主权项

1. An implantable device for measuring an intraocular pressure of an eye having an anterior chamber and a conjunctiva, the implantable device comprising:
a distal portion comprising a pressure sensor, a proximal portion comprising a coil; and a conformable elongate support extending between the distal portion and the coil to couple the distal portion to the coil and wherein the conformable elongate support is sized to position the sensor in the anterior chamber when the proximal portion is positioned under a conjunctiva of the eye, wherein the pressure sensor comprises a pressure transducer for placement in the anterior chamber and responsive to pressure of the anterior chamber and comprises a compliant enclosure encapsulating the pressure sensor, wherein the compliant enclosure is filled with a conformable material comprising one or more of a liquid, viscous material, or gel and the compliant enclosure is configured to be positioned in the anterior chamber such that the conformable material transmits pressure exerted on the compliant enclosure to the pressure transducer, and wherein the conformable material is positioned over the pressure transducer such that pressure exerted on the compliant enclosure in any direction is exerted uniformly on one or more of a first side or a second side of the pressure sensor.