PSEUDOMONAS AERUGINOSA OprM EPITOPES FOR USE IN DIAGNOSTICS AND THERAPEUTICS

摘要

The present invention relates to a peptide antigens derived from Pseudomonas aeruginosa outer membrane protein OprM for use in the diagnosis of Pseudomonas aeruginosa infection and/or prevention/treatment of diseases associated with Pseudomonas aeruginosa infection. Methods of inducing an immune response to Pseudomonas aeruginosa using peptide antigens derived from the OprM outer loops as well as derivatives or fragments thereof are also encompassed by the present invention. Compositions used to practice the methods of the invention are also encompassed.

主权项

1. A composition comprising an immunologically effective amount of one or more polypeptides comprising an outer loop of Pseudomonas aeruginosa (P. aeruginosa) OprM and a pharmaceutically acceptable carrier.