METHOD FOR DIFFERENTIATED IMMUNOMODULATORY THERAPY OF CHRONIC TONSILLITIS AND/OR HYPERTROPHY OF PALATINE TONSILS IN PRESCHOOL CHILDREN

摘要

FIELD: medicine.SUBSTANCE: pathogenetic treatment of chronic tonsillitis and/or hypertrophy of palatine tonsils in preschool children suffering from lymphoproliferative syndrome is ensured by the palatine tonsils debridement. An interleukin-1?(IL-1?) level is measured in the palatine tonsils washing. If the measured value is less than 5.8 pg/ml, recombinant interleukin-1? (IL-1?) is to be administered orally by phonophoresis with the use of the Tonsillor MM apparatus. Two courses of 10 procedures every 14 days are performed. The clinical effectiveness is assessed if observing a positive dynamics of IL-1? measured in the palatine tonsils washing 17 and 41 days after the beginning of the immunomodulatory therapy.EFFECT: higher clinical effectiveness ensured by the differentiated selection of children for carrying out the immunomodulatory therapy, reducing a rate of infectious involvements of the palatine tonsils in the declared group of patients by the pathogenetically reasoned application of recombinant IL-1?.3 cl, 2 tbl, 1 ex