| 发明名称 |
METHODS OF PREPARING ICOTINIB AND ICOTINIB HYDROCHLORIDE, AND INTERMEDIATES THEREOF |
| 摘要 |
The present invention relates to the technical field of medicine, and specifically provides methods for preparing Icotinib, Icotinib hydrochloride, and intermediates thereof. These methods avoid the use of phosphorus oxychloride, thereby greatly reducing the emission of pollutants, which is of major benefits to the economy and environment. |
| 申请公布号 |
US2014343283(A1) |
申请公布日期 |
2014.11.20 |
| 申请号 |
US201214355142 |
申请日期 |
2012.12.28 |
| 申请人 |
BETTA PHARMACEUTICALS CO., LTD. |
发明人 |
Hu Shaojing;Long Wei;Wang Fei;Li Zongquan |
| 分类号 |
C07D491/056;C07D405/04;C07D325/00 |
主分类号 |
C07D491/056 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound of formula A, B, or C: wherein: each of R1 and R2 independently is methyl, ethyl, propyl, or isopropyl; or R1 and R2, together with the N atom to which they are attached, form a 3 to 7-membered ring. |
| 地址 |
Zhejiang CN |
