| 发明名称 |
Methods and Compositions for Modulating Immune Tolerance |
| 摘要 |
The instant invention provides methods and compositions for modulation of the immune system. Specifically, the invention provides methods and compositions for increasing T cell mediated immune response useful in the treatment of cancer and chronic infection. |
| 申请公布号 |
US2014341937(A1) |
申请公布日期 |
2014.11.20 |
| 申请号 |
US201414313481 |
申请日期 |
2014.06.24 |
| 申请人 |
The United States of America, as represented by the Secretary, Department of Health & Human Servic |
发明人 |
Biragyn Arya;Matsushima Kouji;Bataar Dolgor |
| 分类号 |
C07K14/52;C12N9/10;C12N9/22;A61K45/06;C07K14/715 |
主分类号 |
C07K14/52 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for increasing T cell mediated immune response in a subject comprising:
administering to the subject a fusion molecule comprising a chemokine receptor ligand and a toxin moiety; thereby increasing the T cell mediated immune response. |
| 地址 |
Rockville MD US |
