| 发明名称 |
THIOLATED HYALURONAN-BASED HYDROGELS CROSS-LINKED USING OXIDIZED GLUTATHIONE |
| 摘要 |
The invention provides methods, compositions and kits relating to hyaluronan based matrices using oxidized glutathione as a crosslinking agent. |
| 申请公布号 |
US2014341842(A1) |
申请公布日期 |
2014.11.20 |
| 申请号 |
US201414275795 |
申请日期 |
2014.05.12 |
| 申请人 |
BIO TIME, INC. |
发明人 |
Zarembinski Thomas;Erickson Isaac;Doty Nathaniel |
| 分类号 |
A61K47/36;A61K47/42;A61K31/195;C08B37/08;A61K38/19;A61K38/38 |
主分类号 |
A61K47/36 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method of making a hydrogel, the method comprising: 1) contacting a first thiolated monomer with GSSG; 2) allowing the first thiolated monomer and the GSSG to react; and 3) adding a second thiolated monomer to the reaction of step 2), thereby forming a hydrogel comprising the first and second thiolated monomers. |
| 地址 |
Alameda CA US |
