| 发明名称 |
BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF SUBSTITUTED LACTAMS |
| 摘要 |
The present disclosure relates to transaminase polypeptides capable of aminating a dicarbonyl substrate, and polynucleotides, vectors, host cells, and methods of making and using the transaminase polypeptides. |
| 申请公布号 |
US2014342412(A1) |
申请公布日期 |
2014.11.20 |
| 申请号 |
US201214342713 |
申请日期 |
2012.09.07 |
| 申请人 |
Cabirol Fabien;Chen Haibin;Gohel Anupam;Salim Paulina;Smith Derek;Janey Jacob;Kosjek Birgit;Tang Weng Lin;Hsieh Helen;Pham Son |
发明人 |
Cabirol Fabien;Chen Haibin;Gohel Anupam;Salim Paulina;Smith Derek;Janey Jacob;Kosjek Birgit;Tang Weng Lin;Hsieh Helen;Pham Son |
| 分类号 |
C12N9/10;C12P17/12;C12P13/00 |
主分类号 |
C12N9/10 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An engineered transaminase polypeptide comprising an amino acid sequence having at least 80% sequence identity to reference sequence SEQ ID NO:4 and at least an amino acid residue difference as compared to SEQ ID NO:4 at residue position X192. |
| 地址 |
Dusseldorf DE |
