发明名称 |
METHOD FOR PREDICTING CLINICAL EFFECT OF IMMUNOTHERAPY |
摘要 |
Provided is a method for predicting a clinical effect on a subject in a WT1 peptide immunotherapy, said method comprising: a) a step for contacting a sample derived from the subject with WT1 antigen peptide or a variant thereof; and b) a step for detecting the binding of the sample to the WT1 antigen peptide or a variant thereof and thus measuring anti-WT1 antigen peptide IgG antibody titer existing in the sample, characterized in that an increase in the anti-WT1 antigen peptide IgG antibody titer in the subject determines the achievement of a favorable clinical effect. Also provided is a kit for performing the method according to the present invention, said kit containing WT1 antigen peptide or a variant thereof. |
申请公布号 |
CA2912514(A1) |
申请公布日期 |
2014.11.20 |
申请号 |
CA20142912514 |
申请日期 |
2014.05.12 |
申请人 |
INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC. |
发明人 |
SUGIYAMA, HARUO;OJI, YUSUKE |
分类号 |
G01N33/53;A61K39/00;A61P35/00;A61P35/02;C07K7/08;C07K14/82;G01N33/574 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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