发明名称 METHOD FOR LABORATORY ASSESSMENT OF VAGINAL MUCOSA HEALTH IN RADIATION THERAPY OF MALIGNANT NEW GROWTHS WITH UNDERLYING ACCOMPANYING THERAPY
摘要 FIELD: medicine.SUBSTANCE: method involves assessing radioreaction of the vaginal mucosa by visual examination, as well as assessing the vaginal epithelial condition by lactic acid bacilli testing and measuring by bacterioscopical and bacteriological analyses, performing the cytological examination of the surface and intermediate squamose epitheliocytes of the vaginal discharge followed by measuring and finding atrophic and dyskeratotic damages of the above cells. The laboratory examinations precede the radiation exposure and are repeated with the total basic dose (TBD) 20 Gy, 40 Gy and 60 Gy and 1 month after the completion of treatment.EFFECT: invention is characterised by accessibility and low cost of production, and can be used in clinical practice for the purpose of the objective assessment of the vaginal mucosa health in radiation therapy of malignant new growths, particularly for the assessment of the early radiation reactions and injuries of the vaginal mucosa formed in the course of the therapy or in 3 near months thereafter, for the purpose of prediction of the developing radiation complications in the vagina, and if needed, the correction of the radiation exposure regimen, for the purpose of the radiation therapy compliance.1 ex
申请公布号 RU2533240(C1) 申请公布日期 2014.11.20
申请号 RU20130117872 申请日期 2013.04.18
申请人 FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "MOSKOVSKIJ NAUCHNO-ISSLEDOVATEL'SKIJ ONKOLOGICHESKIJ INSTITUT IM. P.A. GERTSENA MINISTERSTVA ZDRAVOOKHRANENIJA ROSSIJSKOJ FEDERATSII" (FGBU "MNIOI IM. P.A. GERTSENA" MINZDRAVA ROSSII) 发明人 BOJKO ANNA VLADIMIROVNA;ERASTOVA ELENA IVANOVNA;DUBOVETSKAJA OKSANA BORISOVNA;MEL'NIKOVA VERA JUR'EVNA;DEMIDOVA LJUDMILA VLADIMIROVNA;DUNAEVA ELENA ANATOL'EVNA
分类号 G01N33/48;C12Q1/06 主分类号 G01N33/48
代理机构 代理人
主权项
地址