| 发明名称 |
Composition Comprising Acetic Anhydride And A Gadolinium Complex, And Method For The Use In Hyperpolarisation In MRI Analysis |
| 摘要 |
The present invention generally relates to a composition comprising acetic anhydride, a DNP agent and a gadolinium complex and its use for the preparation of hyperpolarised imaging agent for MR diagnostic analysis. |
| 申请公布号 |
US2014343402(A1) |
申请公布日期 |
2014.11.20 |
| 申请号 |
US201214362447 |
申请日期 |
2012.12.03 |
| 申请人 |
BRACCO IMAGING S.P.A. |
发明人 |
Aime Silvio;Colombo Serra Sonia;Jensen Pernille Rose;Karlsson Magnus;Lerche Mathilde H.;Tedoldi Fabio;Visigalli Massimo |
| 分类号 |
A61B19/00;A61B5/055;G01R33/28;A61K49/10 |
主分类号 |
A61B19/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising:
acetic anhydride, a DNP agent, and a gadolinium complex of formula (A): wherein: R′, R″ and R′″ are independently selected from: optionally substituted phenyl, (C1-C6)alkylene-phenyl and C6-C10 heterocyclic ring. |
| 地址 |
Milano IT |
