发明名称 |
FORMULATION OF SMALL ADRENERGIC AGONIST SALT FORMS IN ORGANIC SOLVENTS |
摘要 |
Aspects of the present disclosure are directed to formulations that permit the solubilization and long term, stable storage of adrenergic agonist vasoconstrictors in organic solvents. Provided herein are formulations comprising about 250 mM to about 3000 mM of an acid salt of an adrenergic agonist vasoconstrictor dissolved in a pharmaceutically acceptable topical delivery vehicle comprising a water miscible, organic solvent having a water content of less than 40% by weight. Also provide are methods for using and kits containing such formulations. |
申请公布号 |
US2014343159(A1) |
申请公布日期 |
2014.11.20 |
申请号 |
US201214122442 |
申请日期 |
2012.03.09 |
申请人 |
PROCERTUS BIOPHARM, INC. |
发明人 |
Fahl William E. |
分类号 |
A61K47/10;A61K31/138 |
主分类号 |
A61K47/10 |
代理机构 |
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代理人 |
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主权项 |
1. A formulation for topical delivery of a vasoconstrictor to a subject comprising:
about 250 mM to about 3000 mM of an acid salt of an adrenergic agonist vasoconstrictor dissolved in a pharmaceutically acceptable topical delivery vehicle comprising a water miscible, organic solvent having a water content of less than about 40% by weight. |
地址 |
Madison WI US |