| 摘要 |
The present invention relates to compounds corresponding to formula (I) in which: —R1 represents a substituted phenyl; —R2 represents: —a substituted phenyl; —a heteroaromatic group, the said group being unsubstituted or substituted one or more times; —R3 represents a group Alk; —R4 represents a hydrogen atom or a (C1-C4)alkyl; —R5 represents a hydrogen atom, a (C3-C6)cycloalkyl or a (C1-C4)alkyl-O-Alk; —or alternatively R4 and R5, together with the nitrogen atom to which they are attached, constitute a heterocyclic radical chosen from: azetidin-1-yl, pyrrolidin-1-yl, piperid-1-yl, morpholin-4-yl; —R6 represents a group —COOAlk, a group —CONH2 or a group —NHSO2Alk; —Alk represents a (C1-C4)alkyl, which is unsubstituted or substituted one or more times with a halogen atom; in the form of the base or of an acid-addition salt. Preparation process and diagnostic and therapeutic use.; |
| 主权项 |
1. Compound corresponding to formula (I):in which:
R1 represents a phenyl substituted one or more times with substituents independently chosen from a halogen atom, a group -Alk and a group —OAlk; R2 represents:
a phenyl substituted one or more times with substituents independently chosen from a halogen atom, a cyano, a hydroxyl, a nitro, a group -Alk, —OAlk, —SAlk, —SO2Alk, —COAlk, —SO2NR4R5, a —(C1-C6)alkyl-OH, a —(C1-C4)alkyl-COOAlk, a —O—(C1-C4)alkyl-R6, a methylenedioxy and an ethylenedioxy; ora heteroaromatic group, the said group being unsubstituted or substituted one or more times with substituents independently chosen from a halogen atom, a cyano, a group -Alk, a group —OAlk, a group —SAlk or —N(Alk)2; R3 represents a group Alk; R4 represents a hydrogen atom or a (C1-C4)alkyl; R5 represents a hydrogen atom, a (C3-C6)cycloalkyl or a (C1-C4)alkyl-O-Alk; or alternatively R4 and R5, together with the nitrogen atom to which they are attached, constitute a heterocyclic radical chosen from: azetidin-1-yl, pyrrolidin-1-yl, piperid-1-yl, morpholin-4-yl; R6 represents a group —COOAlk, a group —CONH2 or a group —NHSO2Alk; wherein Alk represents a (C1-C4)alkyl, which is unsubstituted or substituted one or more times with a halogen atom;in the form of the base or of an acid-addition salt. |
