MASS SPECTROMETER

摘要

A mass spectrometer including chromatogram creation means for creating a chromatogram showing changes over time in an ion intensity within a predetermined mass range based on the MS analysis results, and timing determination means for determining a timing to perform MS/MS analysis based on the chromatogram. The timing determination means determines, as a timing to perform MS/MS analysis, a point in time at which a signal intensity in the chromatogram reaches a predetermined upper limit after exceeding a predetermined lower limit or a point in time at which a signal intensity in the chromatogram reaches a top of a peak without reaching the upper limit after exceeding the lower limit. It is thus possible to collect precursor ions at a timing at which the signal intensity of a peak originating from sample components is highest between the upper limit and lower limit, thereby obtaining a high quality MS/MS spectrum.

主权项

1. A mass spectrometer which sequentially introduces sample components which are temporally separated by a column of a chromatograph into an ionization unit and performs mass analysis, comprising:
a) MS analysis performing means for repeatedly performing MS analysis on ions generated in the ionization unit; b) chromatogram creation means for creating a chromatogram that shows changes over time in an ion intensity within a predetermined mass range based on a result of the MS analysis; c) timing determination means for determining a timing to perform MS/MS analysis based on a signal intensity in the chromatogram; and d) MS/MS analysis performing means for performing MS/MS analysis in which ions belonging to the mass range among ions generated in the ionization unit are adopted as precursor ions, in accordance with the timing to perform MS/MS analysis that is determined by the timing determination means, wherein: the timing determination means determines, as the timing to perform MS/MS analysis, a point in time at which a signal intensity in the chromatogram reaches a predetermined upper limit after exceeding a predetermined lower limit, or a point in time at which, after exceeding the lower limit, a signal intensity in the chromatogram arrives at a top of a peak without reaching the upper limit.