摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to a pharmaceutical composition for treating type 2 diabetes, which contains (R)-7-[3-amino-4-(2,4,5-trifluorophenyl)-butyryl]-3-trifluoromethyl-,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine-1-carboxylic acid methyl ester or its pharmaceutically acceptable salt, metformin or its salt, and additive agents. Also, the invention refers to a method of treating type 2 diabetes involving administering the above pharmaceutical composition.EFFECT: invention possesses the high efficacy of treating type 2 diabetes and lower toxicity than the known analogues.21 cl, 8 tbl, 7 ex |